{"id":37081,"date":"2020-05-05T15:29:02","date_gmt":"2020-05-05T13:29:02","guid":{"rendered":"\/gruppo5\/?page_id=37081"},"modified":"2022-02-14T16:14:44","modified_gmt":"2022-02-14T15:14:44","slug":"hypothermia-induced-radioprotection","status":"publish","type":"page","link":"\/gruppo5\/en\/hypothermia-induced-radioprotection\/","title":{"rendered":"HYPORAD"},"content":{"rendered":"\n

HYPORAD – HYPOthermia-induced RADioprotection<\/span>

<\/strong><\/span><\/h4>\n\n\n\n

Coordinator: Matteo Negrini<\/a><\/strong>
Duration: <\/strong>2020<\/p>\n

Research group: <\/strong>Cerri Matteo, Sioli Maximiliano, Zoccoli Antonio<\/p>\n\n\n\n

The aim of this project is to investigate if synthetic torpor can provide non-hibernators with an enhanced defence versus radiation damage even after the exposure, and how much of this defence is caused by hypothermia. The project is a natural evolution of HIBRAD (2017-2018), a previous project studying the radio-protection mechanisms of torpor in mammals <\/p>\n

The hypothesis is supported by the observation that\u00a0 hybernators have an enhanced resistance to radiation damage during the period of hypothermia; that non-hibernators subjected to syntetic torpor seem to present the same degree of resistance that hibernators show ; that the protective effect has been shown to be in place even if torpor is induced within three hours after exposure to a lethal dose of radiation.<\/p>\n

If confirmed,\u00a0 this could represent the first effective treatment for acute radiation syndrome – a concrete risk for workers in nuclear plants, nuclear facilities, and for space travellers<\/p>\n

First results are summarized in the following publications:<\/p>\n